Rom Ritthikrai (Mitr Chaibancha) is at a nightclub getting very drunk and trying to persuade others to join him in his fun. He is retrieved by his faithful assistant Oy (Petchara Chaowarat). Rom is actually the masked crimefighter, Insee Daeng, or Red Eagle, and he uses the persona as a fun-loving drunkard as a cover.
Appu (Prashanth) is a taxi driver in Mumbai (Bombay). He is still haunted by the suicide of his sister who was sold to a brothel. He is still trying to find out the culprit. Here he meets Sita (Devayani) who is chased by Eunuch Maharani (Prakash Raj) who is also responsible for the death of his sister. Maharani is the madame or kingpin of the flesh trade in Mumbai. Maharani wants the beautiful Sita for the flesh trade. Appu fights and saves Sita from Maharani. Here his friend Vignesh and his lover Kaveri die saving Appu and Sita.
Amber (Malay name Nurlin) and Lisu are two sisters from China, who have come to Malaysia to further their modelling and singing careers. One day Lisu goes missing, while Amber falls into a coma and is taken back to China for treatment. She awakens five months later with no memory of her past, and returns to Malaysia with her boyfriend, Dino. Amber decides to resume her modelling career and search for Lisu, but finds herself being harassed by an obsessive male fan and haunted by visions of her sister.
Cheila is a transsexual who has come back from Canada to spend holidays at the quinta she bought for her mother years ago, seeking family support before undergoing her sexual reassignment surgery. Upon her arrival she finds the once luxurious house completely deteriorated and inhabited by her lazy and unemployed brothers with their wives and children. The financial problems and chaotic situations surrounding her relatives make her reconsider her relationship with them and herself.
Karuvarai Pookkal, the first Tamil film about transgender people, is a docu-feature film. It illustrates the difficult life and folklore of transgender people in India especially in Tamil Nadu. It portrays the critical situation of the family where a transgender child is born, discusses the difficulties and taboos of bringing up that child, and the difficulties of the child itself.
Three bachelors, Kamal Haasan, Ramesh Arvind and Nassar, stay together and live a happy-go-lucky life. Elsewhere, fifteen-year-old Parvathi (Ruchita Prasad) witnesses her family being murdered by her uncle; she escapes from them to save her life. To avoid getting caught, she disguises herself as a boy and starts living as a servant in the house of these bachelors. Kamal discovers that 'he' is actually a girl. After hearing her story, Kamal and his friends try to protect her from her evil uncle with the help of the policeman (S. P. Balasubrahmanyam) who plots to save her as he still remembers Parvathi who stayed in his house for a brief period as a servant.
The film revolves around Sadarame, a brave woman who dares all the challenges she faces in life and a prince who admires her for her bravery and falls in love with her. She dons a male outfit to escape from a thief with a roving eyes ,called Pucca Kalla. Thinking her to be a male, a princess falls in love with her and a confusion over the characters follows. The films ends up with the prince marrying both Sadarame and the princess.