A student is held up in the library while a riot rages outside. As SDS protesters head to burn the library down, He has to fend them off with his baseball bat. This film opens with actual footage of civil disturbances in the 1960s, and moves on to images of historical American figures.
Through audio interviews and montage sequences, LSD 25 is the travelogue of a young Nova Scotian woman's trip to Montreal in 1995, and the psychotronic meltdown which she underwent there. Stephanie Preyde herself eloquently and unflinchingly narrates the film, describing the cumulative effects of the copious amounts of acid she took during that summer, the ongoing and Byzantine delusions which she suffered (Montreal as the lost City of Atlantis amongst others), the repudiation of her physical self, her eventual institutilization and journey to "normalcy." In this experimental documentary—set to a trippy acid jazz score—Preyde faces the ongoing repercussion of her trips: a possible misdiagnosis of bipolar disorder instead of temporary acid psychosis, and ironically, lifelong reliance on prescription meds.