Un policier, l'inspecteur Danladi Waziri, enquête sur une série de viols et de meurtres de femmes dans une ville de l'Ouest du Nigeria. Les Colonie et Protectorat du Nigeria sont à la veille de l'indépendance du Nigeria, le 1er octobre 1960.
A Mile from Home chronicles the life of a university student, Jude Odaro/Lala (Tope Tedela) who joined a gang in his quest to avenge an injustice meted out to him by Stone, a notorious gangster who forcefully dispossesses him of a precious possession.
The film starts with Samuel Gabriel (Iyke Adiele) falling into the trap of Police-men while trying to sell hard drugs. He tried escaping but was ambushed by several of them. His interrogation at the police station was aborted when the interrogating officer was being blackmailed by his guardian for violating his fundamental human rights some years ago as a minor, After his release he was informed that his sister Emmanuella (Tehilia Adiele) was alive but with a mental condition and asthma. He visited her at the asylum and after much persuasion and assurance he was eventually allowed to take her home.